Andrew Garfield stars as Peter Parker, who gains arachnid-like abilities and confronts the villainous Lizard, while also investigating the mystery of his parents' disappearance in this 2012 superhero film. What is this movie called?

The film described, featuring Andrew Garfield as Peter Parker, who gains spider-like abilities, battles the villainous Lizard, and seeks answers about his parents' disappearance, is indeed "The Amazing Spider-Man (Review)." Released in 2012, this movie served as a reboot of the Spider-Man film franchise, offering a fresh take on the iconic superhero's origin story.

In this iteration, Peter Parker, an outcast high schooler, uncovers a mysterious briefcase belonging to his father, leading him to Oscorp and his father's former partner, Dr. Curt Connors. While at Oscorp, Peter is bitten by a genetically engineered spider, which grants him his extraordinary powers. The film's narrative then sees Connors transform into the Lizard, a formidable reptilian foe, while Peter, as Spider-Man, grapples with his new abilities and the lingering questions surrounding his parents' vanishing act.

"The Amazing Spider-Man" aimed to provide a more grounded and realistic approach to the character. Andrew Garfield's portrayal of Spider-Man was noted for bringing a wise-cracking and sarcastic energy to the role. The film also introduced Gwen Stacy, played by Emma Stone, as Peter's first love interest, a character prominent in the Spider-Man comic books. This movie marked a new chapter for the web-slinger on the big screen, exploring both Peter's superheroics and his personal quest for truth.