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In human genetics, biological sex is determined by a pair of chromosomes. While males have one X and one Y chromosome (XY), females typically possess two X chromosomes (XX). This XX pairing means the X chromosome is directly associated with the development of female characteristics. Every embryo begins with the potential to develop along either path, and it is the specific combination of these chromosomes that directs the outcome.
The key is actually the presence or absence of the Y chromosome. The Y chromosome, though much smaller than the X, carries a critical gene called the SRY gene. This gene acts as a "master switch" that triggers the development of male traits. If an embryo does not have a Y chromosome and its SRY gene, it will naturally proceed along the female developmental pathway, guided by its two X chromosomes.
Interestingly, the X chromosome is much larger and contains over a thousand genes that are essential for everyone, regardless of sex. These genes are involved in everything from brain development to blood clotting. Because a mother's egg always contributes an X chromosome, it is the father's sperm, which can carry either an X or a Y, that ultimately determines the biological sex of the child.
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