This Syfy series follows U.S. Secret Service agents who retrieve and safeguard supernatural artifacts in a massive, top-secret government facility.

The Syfy series that involves U.S. Secret Service agents collecting and safeguarding supernatural (Review) artifacts in a massive, top-secret government facility is "Warehouse 13". The show, which premiered in 2009, centers on Secret Service Agents Myka Bering and Pete Lattimer, who are reassigned to a remote, covert warehouse in South Dakota. This facility, known as Warehouse 13, is the latest in a long line of similar repositories throughout history, designed to house dangerous and powerful relics.

Myka and Pete's new assignment involves traveling the world to investigate reports of paranormal activity, retrieve new artifacts, and ensure existing ones remain secured. These artifacts, often linked to historical figures or events, possess unique and sometimes chaotic abilities, ranging from a comb belonging to Lucrezia Borgia that can possess its wearer, to more powerful items capable of widespread destruction. The agents, alongside their eccentric supervisor Artie Nielsen and later joined by tech whiz Claudia Donovan and agent Steve Jinks, work to prevent these objects from falling into the wrong hands or causing havoc.

The series blends elements of science fiction, mystery, and comedy, often drawing comparisons to The X-Files (Review) and "Raiders of the Lost Ark". "Warehouse 13" ran for five seasons, captivating audiences with its intriguing premise, character development, and the clever integration of historical references into its fantastical narratives. The show also explored a shared fictional universe with other Syfy series like "Eureka," with character crossovers adding an extra layer of connectivity for fans.