Which 2016 X-Men film, directed by Bryan Singer, features the ancient mutant Apocalypse awakening to reshape the world, leading the X-Men to unite against him?

The 2016 film X-Men: Apocalypse (Review) is indeed the correct answer, featuring the ancient and immensely powerful mutant En Sabah Nur, also known as Apocalypse. Directed by Bryan Singer, this installment in the X-Men film series sees Apocalypse awaken in 1983 after thousands of years entombed in ancient Egypt. Horrified by the state of the modern world, he plans to cleanse it and reshape it in his own image, gathering a team of powerful mutants, his "Four Horsemen," to aid him in this destructive goal.

The film, which is a direct sequel to "X-Men: Days of Future Past (Review)," continues the narrative with the younger cast of mutants, including James McAvoy as Professor Charles Xavier, Michael Fassbender as Magneto, and Jennifer Lawrence as Mystique. As Apocalypse begins his global assault, the X-Men must unite to stop him, leading to a climactic battle where they confront his overwhelming power and his mission to eradicate humanity. This film marks Bryan Singer's fourth time directing an X-Men movie, showcasing his continued involvement in shaping the cinematic universe of these Marvel characters.

"X-Men: Apocalypse" delves into the origins of mutants and introduces younger versions of iconic characters such as Cyclops, Jean Grey, and Storm, who join the seasoned heroes in their fight for survival. The movie explores themes of loyalty, survival, and identity against a backdrop of comic-book spectacle. Its release in May 2016 further expanded the intricate timeline of the X-Men franchise, setting the stage for subsequent films.